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Osobe koje pokazuju suicidalne tendencije ne smeju imati pristup većim količinama diazepama zbog rizika od predoziranja.
Usporen metabolizam diazepama dovodi do produženja poluvremena eliminacije i povećanja koncentracije diazepama u plazmi. Usporena je eliminacija N-demetil metabolita diazepama, što može značajno pojačati sedativni efekat. Povećan je rizik od inhibicije CNS, npr. sedacije.
Experience dizzy If co-codamol can make you feel dizzy when you rise up, check out having up pretty slowly but surely or stay sitting down down right up until you feel improved. If you start to come to feel dizzy, lie down so you tend not to faint, then sit right up until you're feeling superior.
Diazepam se ne sme primenjivati kao jedini lek u terapiji depresije ili anksioznosti udružene sa depresijom, jer kod ovih pacijenata može da se izazove suicid.
Istovremena primena sa rifampicinom značajno snižava koncentraciju diazepama, što smanjuje njegov efekat. Potrebno je izbegavati istovremenu primenu rifampicina i diazepama.
Lek ima snažan uticaj na psihofizičke sposobnosti, za vreme terapije nije dozvoljeno upravljanje vozilom, niti rad sa mašinama.
Kada se koriste benzodiazepini dugog dejstva, važno je upozoriti da se ne prelazi na primenu benzodiazepina kratkog dejstva, jer mogu da se razviju simptomi obustave.
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Dry mouth Try out chewing sugar-free gum or sucking sugar-totally free sweets. You can even get or a health care provider could prescribe a man-made saliva substitute to keep the mouth moist. This will come as being a spray, gel or lozenge and can be bought from the pharmacy.
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Diazepam is usually applied IV or rectally being an anticonvulsant, and IV diazepam or lorazepam commonly are considered the medicine of option for termination of standing epilepticus. /Included in US solution label/
Ukoliko se diazepam primenjuje istovremeno sa drugim lekovima sa centralnim dejstvom neophodno je imati u vidu farmakološka svojstva lekova; click here poseban oprez je neophodan ako su u pitanju supstance koji mogu pojačati dejstvo ili biti pojačane dejstvom diazepama kao što su neuroleptici, anksiolitici/sedativi, hipnotici, antidepresivi, antikonvulzivi, sedativni antihistaminici, antipsihotici, anestetici za opštu anesteziju i narkotički analgetici. Istovremena primena sa ovim lekovima može pojačati sedativni efekat i uzrokovati depresiju